Large Pharmas
How Locust Walk Engages with Large Pharma Companies
Framework for External Innovation
External innovation comes in various forms and sizes for internalizing or externalizing technologies based on development stages and strategic alignment with corporate objectives.
Capabilities and Bandwidth
Internalization: Accessing innovation from external partners.
Externalization: Placing internal programs with external partners.
Stage of Development
Support across all development stages, from discovery to commercial.
Therapy Area
Align innovations with the company's capabilities and long-term interests across various therapy areas.
Capabilities and Bandwidth
- Internalization: Accessing innovation from external partners.
- Externalization: Placing internal programs with external partners.
Stage of Development
- Support across all development stages, from discovery to commercial
Therapy Area
- Align innovations with the company's capabilities and long-term interests across various therapy areas.
Internalization Goals: Partnering with Large Pharma
At Locust Walk, we support large pharmaceutical companies in achieving their internalization goals through strategic and comprehensive solutions.
New Company Incubation & Formation
- Provide a playbook for starting companies from academic research.
- Align NewCo incubation with corporate development strategies and offer guidance for incubator occupants.
- Provide a playbook for starting companies from academic research.
- Align NewCo incubation with corporate development strategies and offer guidance for incubator occupants.
Corporate Venture Capital Investment Model
- Develop investment models, including selection criteria and capitalization plans.
- Ensure investment criteria align with broader corporate development goals and avoid financial consolidation issues.
- Develop investment models, including selection criteria and capitalization plans.
- Ensure investment criteria align with broader corporate development goals and avoid financial consolidation issues.
Access Early-Stage Technologies & Capabilities
- Offer structured options for in-licensing, asset purchase, and M&A deals, including co-development/co-promotion playbooks.
- Provide structural considerations for platform deals and support deal processes.
- Formulate technology innovation strategies and analyze acquisition vs. partnership trade-offs.
- Provide structural considerations for platform deals and support deal processes.
Access Clinical & Late-Stage Assets & Capabilities
- Conduct global and regional asset and company screens to identify L&A targets and perform due diligence and valuation modeling.
- Offer structured options for in-licensing, asset purchase, and M&A deals, including co-development/co-promotion playbooks.
- Conduct global and regional asset/company screens and perform due diligence and valuation modeling.
- Offer structured options for in-licensing, asset purchase, and M&A deals, including co-development playbooks.
- Internalization Goals: Partnering with Large Pharma
Access Clinical & Late-Stage Assets & Capabilities
- Conduct global and regional asset and company screens to identify L&A targets and perform due diligence and valuation modeling.
- Offer structured options for in-licensing, asset purchase, and M&A deals, including co-development/co-promotion playbooks.
Access Early-Stage Technologies & Capabilities
- Formulate technology innovation strategies and analyze acquisition vs. partnership trade-offs.
- Provide structural considerations for platform deals and support deal processes.
New Company Incubation & Formation
- Provide a playbook for starting companies from academic research.
- Align NewCo incubation with corporate development strategies and offer guidance for incubator occupants.
Corporate Venture Capital Investment Model
- Develop investment models, including selection criteria and capitalization plans.
- Ensure investment criteria align with broader corporate development goals and avoid financial consolidation issues.
- Externalization Goals: Leveraging Partnerships and Finance
Stand up NewCos with Assets and/or Platforms
- Design spinoff strategies, including licensing and portfolio management.
- Prepare management presentations, secure capital from investors, and recruit management teams.
Externalize Core Assets with Partners
- Develop corporate development and partnering strategies, including co-development/co-promotion playbooks.
- Provide valuation and terms modeling, and support transaction processes.
Externalize Non-Core Assets with Partners
- Formulate strategies for partnering non-core assets and provide valuation and terms modeling.
- Support processes for out-licensing, joint ventures, or co-development/co-promotion arrangements.
Seek Project Finance to Reduce R&D Expense
- Structure project finance terms and support deal processes to secure financing.
- Offer valuation and terms modeling to optimize financial outcomes.
Externalization Goals: Leveraging Partnerships and Finance
Locust Walk helps large pharma companies achieve externalization goals by maximizing asset value and securing necessary financing.
Stand up NewCos with Assets and/or IP
- Design spinoff strategies, including licensing and portfolio management.
- Prepare management presentations, secure capital from investors, and recruit management teams.
- Design spinoff strategies, including licensing and portfolio management.
- Prepare management presentations, secure capital from investors, and recruit management teams.
Externalize Core Assets with Partners
- Develop corporate development and partnering strategies, including co-development playbooks.
- Provide valuation and terms modeling, and support transaction processes.
- Develop corporate development and partnering strategies, including co-development/co-promotion playbooks.
- Provide valuation and terms modeling, and support transaction processes.
Externalize Non-Core Assets with Partners
- Formulate strategies for partnering non-core assets and provide valuation and terms modeling.
- Support processes for out-licensing, joint ventures, or co-development/co-promotion arrangements.
- Formulate strategies for partnering non-core assets and provide valuation and terms modeling.
- Support processes for out-licensing, joint ventures, or co-development arrangements.
Seek Project Finance to Reduce R&D Expense
- Structure project finance terms and support deal processes to secure financing.
- Offer valuation and terms modeling to optimize financial outcomes.
- Structure project finance terms and support deal processes to secure financing.
- Offer valuation and terms modeling to optimize financial outcomes.
By leveraging Locust Walk’s expertise, large pharmaceutical companies can effectively internalize new ventures and externalize assets through strategic partnerships and financing, driving innovation and growth.