Transaction Case Studies
GLOBAL DEVELOPMENT AND COMMERCIALIZATION AGREEMENT FOR NOVEL CANCER THERAPEUTIC
CLIENT: Ascenta
PARTNER: Debiopharm Group
TRANSACTION:
Worldwide Licensing Agreement for AT-406
Situation Assessment
- Ascenta is a privately-held, clinical stage biopharmaceutical company dedicated to the discovery and development of novel orally- active, small molecule drugs that restore the natural potential for cancer cells to undergo cell death (apoptosis).
- Lead program, AT-406, a novel multi-IAP inhibitor, currently in dose escalating phase 1 clinical testing.
- Engaged Locust Walk Partners as its exclusive business and corporate development advisor.
Key Activities
- Revised and prepared high impact teaser and management presentation
- Led an outreach to >80 leading global and regional companies, both publicly traded and privately held, that are active in the development and commercialization of oncology products.
- Created forecast model for early stage targeted oncology asset, which aided in deal negotiations and offer comparison
- Led multiple parties through a confidential diligence process leading to competing term sheets.
- Conducted face-to-face negotiations of the term sheet and definitive agreement.
Successful Outcome
- Competitive process resulted in multiple term sheets and an exclusive global partnership for AT-406.